Membranski transkripcioni faktor peptidaza, mesto 1
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| Membranski transkripcioni faktor peptidaza, mesto 1 | |
|---|---|
| Identifikatori | |
| Simbol | MBTPS1 |
| Alt. simboli | S1P |
| Entrez | 8720 |
| Hugo | 15456 |
| OMIM | 603355 |
| RefSek | NM_003791 |
| UniProt | Q14703 |
| Drugi podaci | |
| EC broj | 3.4.21.112 |
| Lokus | Hrom. 16 q24 |
Membranski transkripcioni faktor peptidaza, mesto 1, takođe poznata kao Mesto-1 proteaza (engl. Site-1 Protease - S1P), je enzim (EC 3.4.21.112) kodiran MBTPS1 genom koji koji odseca petlju endoplazmatičnog retikuluma od transkripcionog faktora vezujućeg proteina sterolnog regulatornog elementa (SREBP).[1][2]
Vidi još[uredi | uredi kod]
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- ↑ Brown MS, Goldstein JL (1999). „A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood”. Proc. Natl. Acad. Sci. U.S.A. 96 (20): 11041–8. DOI:10.1073/pnas.96.20.11041. PMC 34238. PMID 10500120.
- ↑ Nakajima T, Iwaki K, Kodama T, Inazawa J, Emi M (2000). „Genomic structure and chromosomal mapping of the human site-1 protease (S1P) gene”. J. Hum. Genet. 45 (4): 212–7. DOI:10.1007/s100380070029. PMID 10944850.