Manozilglikoproteinska endo-beta-manozidaza
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| Manozilglikoprotein endo-beta-manozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.152 | ||||||||
| CAS broj | 141176-95-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Manozilglikoprotein endo-beta-manozidaza (EC 3.2.1.152, endo-beta-manozidaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza alfa-D-manozil-(1->6)-beta-D-manozil-(1->4)-N-acetil-beta-D-glukozaminil-(1->4)-N-acetil-beta-D-glukozaminil sekvence glikoproteina do alfa-D-manozil-(1->6)-D-manoze i N-acetil-beta-D-glukozaminil-(1->4)-N-acetil-beta-D-glukozaminil sekvenci
The supstratna grupa je supstituent na N-4 asparaginskog ostataka glikoproteina.
Reference[uredi | uredi kod]
- ↑ Ishimizu, T., Sasaki, A., Okutani, S., Maeda, M., Yamagishi, M. and Hase, S. (2004). „Endo-β-mannosidase, a plant enzyme acting on N-glycan. Purification, molecular cloning, and characterization”. J. Biol. Chem. 279: 38555-38562. PMID 15247239.
- ↑ Sasaki, A., Yamagishi, M., Mega, T., Norioka, S., Natsuka, S. and Hase, S. (1999). „Partial purification and characterization of a novel endo-β-mannosidase acting on N-linked sugar chains from Lilium longiflorum thumb”. J. Biochem. (Tokyo) 125: 363-367. PMID 9990135.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.