Limulusni faktor grušavanja C

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Limulusni faktor grušavanja C
Identifikatori
EC broj 3.4.21.84
CAS broj 115743-27-6
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Limulusni faktor grušavanja C (EC 3.4.21.84, faktor C, limulusni faktor C) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Selektivno razlaganje -Arg103-Ser- i -Ile124-Ile- veza u limulusnom faktoru zguršavanja B čime se formira faktor overbar B. Razlaganje -Pro-Arg- veza u sintetičkim supstratima

Ovaj enzim je izolovan iz hemocitnih granula vrsta rakova Limulus i Tachypleus.

Reference[uredi - уреди | uredi izvor]

  1. Nakamura, T., Morita, T. and Iwanaga, S. (1986). "Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization". Eur. J. Biochem. 154: 511–521. PMID 3512266. 
  2. Muta, T., Miyata, T., Misumi, Y., Tokunaga, F., Nakamura, T., Toh, Y., Ikehara, Y. and Iwanaga, S. (1991). "Limulus factor C. An endotoxin-sensitive serine protease zymogen with a mosaic structure of complement-like, epidermal growth factor-like, and lectin-like domains". J. Biol. Chem. 266: 6554–6561. PMID 2007602. 
  3. Tokunaga, F., Nakajima, H. and Iwanaga, S. (1991). "Further studies on lipopolysaccharide-sensitive serine protease zymogen (factor C): its isolation from Limulus polyphemus hemocytes and identification as an intracellular zymogen activated by α-chymotrypsin, not by trypsin". J. Biochem. (Tokyo) 109: 150–157. PMID 2016264. 

Literatura[uredi - уреди | uredi izvor]

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