LP-211

LP-211
(IUPAC) ime
	N-(4-cijanofenilmetil)-4-(2-difenil)-1-piperazinheksanamid
Klinički podaci
Identifikatori
ATC kod	nije dodeljen
PubChem	25107716
Hemijski podaci
Formula	C30H34N4O
Mol. masa	466,616 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C30H34N4O/c31-23-25-14-16-26(17-15-25)24-32-30(35)13-5-2-8-18-33-19-21-34(22-20-33)29-12-7-6-11-28(29)27-9-3-1-4-10-27/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-22,24H2,(H,32,35) ; Key: BQEDZLDNNBDKDS-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

LP-211 je lek koji deluje kao potentan i selektivan agonist 5HT₇ serotoninskog receptora, sa boljom moždanom penetracijom od starijih 5-HT₇ agonista u istoj seriji, i sličnim dejstvom na životinje.^[3]^[4]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hedlund PB, Leopoldo M, Caccia S, Sarkisyan G, Fracasso C, Martelli G, Lacivita E, Berardi F, Perrone R (August 2010). „LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor”. Neuroscience Letters 481 (1): 12–6. DOI:10.1016/j.neulet.2010.06.036. PMC 2910240. PMID 20600619.
↑ Monti JM (August 2011). „Serotonin control of sleep-wake behavior”. Sleep Medicine Reviews 15 (4): 269–81. DOI:10.1016/j.smrv.2010.11.003. PMID 21459634.

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[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[pmid20600619-3] Hedlund PB, Leopoldo M, Caccia S, Sarkisyan G, Fracasso C, Martelli G, Lacivita E, Berardi F, Perrone R (August 2010). „LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor”. Neuroscience Letters 481 (1): 12–6. DOI:10.1016/j.neulet.2010.06.036. PMC 2910240. PMID 20600619.

[pmid21459634-4] Monti JM (August 2011). „Serotonin control of sleep-wake behavior”. Sleep Medicine Reviews 15 (4): 269–81. DOI:10.1016/j.smrv.2010.11.003. PMID 21459634.

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LP-211

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