L-pipekolat oksidaza
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| L-pipekolat oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.3.7 | ||||||||
| CAS broj | 81669-65-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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L-pipekolat oksidaza (EC 1.5.3.7, pipekolatna oksidaza, L-pipekolna kiselina oksidaza) je enzim sa sistematskim imenom L-pipekolat:kiseonik 1,6-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-pipekolat + O2 (S)-2,3,4,5-tetrahidropiridin-2-karboksilat + H2O2
Produkt reaguje sa vodom i formira (S)-2-amino-6-oksoheksanoat.
Reference[uredi | uredi kod]
- ↑ Baginsky, B.L. and Rodwell, V.W. (1967). „Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase”. J. Bacteriol. 94: 1034-1039. PMID 6051341.
- ↑ Kinzel, J.J. and Bhattacharjee, J.K. (1982). „Lysine biosynthesis in Rhodotorula glutinis: properties of pipecolic acid oxidase”. J. Bacteriol. 151: 1073-1077. PMID 6809728.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.