L-lizin 6-transaminaza
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| L-lizin 6-transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.36 | ||||||||
| CAS broj | 9054-68-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
L-lizin 6-transaminaza (EC 2.6.1.36, lizinska 6-aminotransferaza, lizinska epsilon-aminotransferaza, lizinska epsilon-transaminaza, lizin:2-ketoglutarat 6-aminotransferaza, L-lizin-alfa-ketoglutaratna aminotransferaza, L-lizin-alfa-ketoglutaratna 6-aminotransferaza) je enzim sa sistematskim imenom L-lizin:2-oksoglutarat 6-aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je piridoksal-fosfatni protein. Produkt (L-alizin) se konvertuje u intramolekuski dehidriranu formu, (S)-2,3,4,5-tetrahidropiridin-2-karboksilat.
Reference[uredi | uredi kod]
- ↑ Soda, K., Misono, H. and Yamamoto, T. (1968). „L-Lysine:α-ketoglutarate aminotransferase. I. Identification of a product, δ-1-piperideine-6-carboxylic acid”. Biochemistry 7: 4102-4109. PMID 5722275.
- ↑ Soda, K. and Misono, H. (1968). „L-Lysine: α-ketoglutarate aminotransferase. II. Purification, crystallization, and properties”. Biochemistry 7: 4110-4119. PMID 5722276.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.