L-iduronidaza
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| L-iduronidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.76 | ||||||||
| CAS broj | 9073-56-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
L-iduronidaza (EC 3.2.1.76, alfa-L-iduronidaza) je enzim sa sistematskim imenom glikozaminoglikan alfa-L-iduronohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza nesulfatisanih alfa-L-iduronozidnih veza u dermatan sulfatu
Reference[uredi | uredi kod]
- ↑ Matalon, R., Cifonelli, J.A. and Dorfman, A. (1971). „L-Iduronidase in cultured human fibroblasts and liver”. Biochem. Biophys. Res. Commun. 42: 340-345. PMID 4993544.
- ↑ Rome, L.H., Garvin, A.J. and Neufeld, E.F. (1978). „Human kidney α-L-iduronidase: purification and characterization”. Arch. Biochem. Biophys. 189: 344-353. PMID 30407.
- ↑ Srivastava, R.M., Hudson, N., Seymour, F.R. and Weissman, B. (1978). „Preparation of (aryl α-L-idopyranosid)uronic acids”. Carbohydr. Res. 60: 315-326.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.