L-3-cijanoalaninska sintaza
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| L-3-cijanoalaninska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.4.1.9 | ||||||||
| CAS broj | 9059-53-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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L-3-cijanoalaninska sintaza (EC 4.4.1.9, beta-cijanoalaninska sintaza, beta-cijanoalaninska sintetaza, beta-cijano-L-alaninaka sintaza, L-cistein hidrogen-sulfid-lijaza (dodaje HCN)) je enzim sa sistematskim imenom L-cistein vodonik-sulfid-lijaza (dodaje vodonik cijanid, formira L-3-cijanoalanin).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-cistein + Cijanovodonična kiselina L-3-cijanoalanin + vodonik sulfid
Ovaj enzim sadrži piridoksal fosfat.
Reference[uredi | uredi kod]
- ↑ Akopyan, T.N., Braunstein, A.E. and Goryachenkova, E.V. (1975). „β-Cyanoalanine synthase: purification and characterization”. Proc. Natl. Acad. Sci. USA 72: 1617-1621. PMID 1055433.
- ↑ Castric, P.A. and Conn, E.E. (1971). „Formation of β-cyanoalanine by O-acetylserine sulfhydrylase”. J. Bacteriol. 108: 132-136. PMID 5001194.
- ↑ Hendrickson, H.R. (1968). „The β-cyanoalanine synthase of blue lupine”. Fed. Proc. 27: 593-593.
- ↑ Hendrickson, H.R. and Conn, E.E. (1969). „Cyanide metabolism in higher plants. IV. Purification and properties of the β-cyanoalanine synthase of blue lupine”. J. Biol. Chem. 244: 2632-2640. PMID 5769995.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.