Kalikrein plazme

Izvor: Wikipedia
Kalikrein plazme
Identifikatori
EC broj 3.4.21.34
CAS broj 410538-33-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Kalikrein plazme (EC 3.4.21.34, kininogenin, kalikrein I, kalikrein II, kininogenaza, kalikrein, kalikrein, glumorin, padreatin, padutin, kalidinogenaza, bradikininogenaza, pankeasni kalikrein, onokrein P, dilminal D, depot-Padutin, urokalikrein, urinarni kalikrein) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

Selectivno razlaganje pojedinih tipova Arg- i Lys- veza, uključujući Lys-Arg - Arg-Ser i (ljudskom) kininogenu čime se oslobađa bradikinin

Ovaj enzim se formira iz prokalikreina iz plazme dejstvom faktora XIIa.

Reference[uredi - уреди]

  1. Heimark, R.L. and Davie, E.W. (1981). "Bovine and human plasma prekallikrein". Methods Enzymol. 80: 157–172. PMID 6918767. 
  2. McRae, B.J., Kurachi, K., Heimark, R.L., Fujikawa, K., Davie, E.W. and Powers, J.C. (1981). "Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates". Biochemistry 20: 7196–7206. PMID 6976185. 
  3. Silverberg, M. and Kaplan, A.P. (1988). "Prekallikrein". Methods Enzymol. 163: 85–95. PMID 3237096. 
  4. Seidah, N.G., Ladenheim, R., Mbikay, M., Hamelin, J., Lutfalla, G., Rougeon, F., Lazure, C. and Chrétien, M. (1989). "The cDNA structure of rat plasma kallikrein". DNA 8: 563–574. PMID 2598771. 
  5. Tsuda, Y., Teno, N., Okada, Y., Wanaka, K., Bohgaki, M., Hijikata-Okunomiya, A., Okamoto, U., Naito, T. and Okamoto, S. (1989). "Synthesis of tripeptide chloromethyl ketones and examination of their inhibitory effects on plasmin and plasma kallikrein". Chem. Pharm. Bull. 37: 3108–3111. PMID 2534361. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]