Juvenilna-hormonska estaraza
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| Juvenilna-hormonska estaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.59 | ||||||||
| CAS broj | 50812-15-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Juvenilna-hormonska estaraza (EC 3.1.1.59, JH-esteraza, juvenilni hormon analog esteraza, juvenilni hormon karboksiesteraza) je enzim sa sistematskim imenom metil-(2E,6E)-(10R,11S)-10,11-epoksi-3,7,11-trimetiltrideka-2,6-dienoat acilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- metil (2E,6E)-(10R,11S)-10,11-epoksi-3,7,11-trimetiltrideka-2,6-dienoat + H2O (2E,6E)-(10R,11S)-10,11-epoksi-3,7,11-trimetiltrideka-2,6-dienoat + metanol
Ovaj enzim demetiliše hormone mladih insekata, JH1 i JH3.
Reference[uredi | uredi kod]
- ↑ de Kort, C.A.D. and Granger, N.A. (1981). „Regulation of the juvenile hormone titer”. Annu. Rev. Entomol. 26: 1-28.
- ↑ Mitsui, T., Riddiford, L.M. and Bellamy, G. (1979). „Metabolism of juvenile hormone by the epidermis of the tobacco hornworm (Manduca sexta)”. Insect Biochem. 9: 637-643.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.