Indol 2,3-dioksigenaza
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| Indol 2,3-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.17 | ||||||||
| CAS broj | 37256-57-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Indol 2,3-dioksigenaza (EC 1.13.11.17, indolna oksidaza, indolaminska 2,3-dioksigenaza (nespecifična), indol:O2 oksidoreduktaza, indol-kiseonik 2,3-oksidoreduktaza (deciklizacija), IDO (nespecifična)) je enzim sa sistematskim imenom indol:kiseonik 2,3-oksidoreduktaza (deciklizacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- indol + O2 2-formilaminobenzaldehid
Enzim iz biljke Jasminum grandiflorum je flavoprotein koji sadrži bakar, i formira antranilat kao krajnji produkt.
Reference[uredi | uredi kod]
- ↑ Divakar, N.G., Subramanian, V., Sugumaran, M. and Vaidyanathan, C.S. (1979). „Indole oxygenase from the leaves of Jasminum grandiflorum”. Plant Sci. Lett. 15: 177-181.
- ↑ Kunapuli, S.P. and Vaidyanathan, C.S. (1983). „Purification and characterization of a new indole oxygenase from the leaves of Tecoma stans L”. Plant Physiol. 71: 19-23. PMID 16662784.
- ↑ Nair, P.M. and Vaidyanathan, C.S. (1964). „An indole oxidase isolated from the leaves of Tecoma stans”. Biochim. Biophys. Acta 81: 496-506. PMID 14170321.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.