Holoil-KoA hidrolaza
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| Holoil-KoA hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.2.27 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Holoil-KoA hidrolaza (EC 3.1.2.27, PTE-2, holoil-koenzim A tioesteraza, henodezoksiholoil-koenzim A tioesteraza, peroksizomalna acil-KoA tioesteraza 2) je enzim sa sistematskim imenom holoil-KoA hidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- holoil-KoA + H2O holat + KoA
Ovaj enzim takođe deluje na henodezoksiholoil-KoA i u manjoj meri na acil-KoA lanaca kratke i srednje dužine.
Reference[uredi | uredi kod]
- ↑ Hunt, M.C., Solaas, K., Kase, B.F. and Alexson, S.E. (2002). „Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism”. J. Biol. Chem. 277: 1128-1138. PMID 11673457.
- ↑ Solaas, K., Sletta, R.J., Soreide, O. and Kase, B.F. (2000). „Presence of choloyl- and chenodeoxycholoyl-coenzyme A thioesterase activity in human liver”. Scand. J. Clin. Lab. Invest. 60: 91-102. PMID 10817395.
- ↑ Russell, D.W. (2003). „The enzymes, regulation, and genetics of bile acid synthesis”. Annu. Rev. Biochem. 72: 137-174. PMID 12543708.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.