Histon-arginin N-metiltransferaza
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| Histon-arginin N-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.125 | ||||||||
| CAS broj | 445295-80-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Histon-arginin N-metiltransferaza (EC 2.1.1.125, histon proteinska metilaza I, nuklearno proteinska (histonska) N-metiltransferaza, proteinska metilaza I, S-adenozil-L-metionin:histon-arginin omega-N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:histon-arginin Nomega-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim forma Nomega-monometil- i Nomega,Nomega'-dimetil.
Reference[uredi | uredi kod]
- ↑ Rajpurohit, R., Lee, S.O., Paik, W.K., Kim, S. (1994). „Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine: histone-arginine-N-methyltransferase”. J. Biol. Chem. 269: 1075-1082. PMID 8288564.
- ↑ Rawal, N., Rajpurohit, R., Paik, W.K., Kim, S. (1994). „Purification and characterization of S-adenosylmethionine-protein-arginine-N-methyltransferase from rat liver”. Biochem. J. 300: 483-489. PMID 8002954.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.