Hepoksilin-epoksidna hidrolaza
(Preusmjereno sa stranice Hepoksilin-epoksid hidrolaza)
| Hepoksilin-epoksidna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.3.2.7 | ||||||||
| CAS broj | 122096-98-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Hepoksilin-epoksidna hidrolaza (EC 3.3.2.7, hepoksilin epoksidna hidrolaza, hepoksilinska hidrolaza, hepoksilinska A3 hidrolaza) je enzim sa sistematskim imenom (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoksi-8-hidroksiikosa-5,9,14-trienoatna hidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hepoksilin A3 + H2O trioksilin A3
Ovaj enzim konvertuje hepoksilin A3 u trioksilin A3.
Reference[uredi | uredi kod]
- ↑ Pace-Asciak, C.R. (1988). „Formation and metabolism of hepoxilin A3 by the rat brain”. Biochem. Biophys. Res. Commun. 151: 493-498. PMID 3348791.
- ↑ Pace-Asciak, C.R. and Lee, W.-S. (1989). „Purification of hepoxilin epoxide hydrolase from rat liver”. J. Biol. Chem. 264: 9310-9313. PMID 2722835.
- ↑ Fretland, A.J. and Omiecinski, C.J. (2000). „Epoxide hydrolases: biochemistry and molecular biology”. Chem. Biol. Interact. 129: 41-59. PMID 11154734.
- ↑ Newman, J.W., Morisseau, C. and Hammock, B.D. (2005). „Epoxide hydrolases: their roles and interactions with lipid metabolism”. Prog. Lipid Res. 44: 1-51. PMID 15748653.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.