Glikoproteinska endo-alfa-1,2-manozidaza
(Preusmjereno sa stranice Glikoprotein endo-a-1,2-manozidaza)
| Glikoproteinska endo-alfa-1,2-manozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.130 | ||||||||
| CAS broj | 108022-16-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glikoproteinska endo-alfa-1,2-manozidaza (EC 3.2.1.130, glukozilmanozidaza, endo-alfa-D-manozidaza, endo-alfa-manozidaza, endomanozidaza, glukozilna manozidaza) je enzim sa sistematskim imenom glikoprotein glukozilmanohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza terminalnih alfa-D-glukozil-(1,3)-D-manozilnih jedinica sa GlcMan9(GlcNAc)2 oligosaharidne komponente glikoproteina formiranoj na Goldžijevoj membrani
Ovaj enzim učestvuje u sintezi glikoproteina.
Reference[uredi | uredi kod]
- ↑ Lubas, W.A. and Spiro, R.G. (1987). „Golgi endo-α-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme”. J. Biol. Chem. 262: 3775-3781. PMID 3818665.
- ↑ Tulsiani, D.R.P., Coleman, V.P. and Touster, O. (1990). „Asparagine-linked glycoprotein biosynthesis in rat brain: identification of glucosidase I, glucosidase II, and endomannosidase (glucosyl mannosidase)”. Arch. Biochem. Biophys. 277: 114-121. PMID 2407194.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.