GlcA-beta-(1-2)-D-Man-alfa-(1-3)-D-Glc-beta-(1-4)-D-Glc-alfa-1-difosfo-ditrans,oktacis-undekaprenol 4-beta-manoziltransferaza
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| GlcA-beta-(1->2)-D-Man-alfa-(1->3)-D-Glc-beta-(1->4)-D-Glc-alfa-1-difosfo-ditrans,oktacis-undekaprenol 4-beta-manoziltransferaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 2.4.1.251 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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GlcA-beta-(1->2)-D-Man-alfa-(1->3)-D-Glc-beta-(1->4)-D-Glc-alfa-1-difosfo-ditrans,oktacis-undekaprenol 4-beta-manoziltransferaza (EC 2.4.1.251, GumI) je enzim sa sistematskim imenom GDP-manoza:GlcA-beta-(1->2)-D-Man-alfa-(1->3)-D-Glc-beta-(1->4)-D-Glc-alfa-1-difosfo-ditrans,oktacis-undekaprenol 4-beta-manoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- GDP-manoza + GlcA-beta-(1->2)-D-Man-alfa-(1->3)-D-Glc-beta-(1->4)-D-Glc-alfa-1-difosfo-ditrans,oktacis-undekaprenol GDP + D-Man-beta-(1->4)- GlcA-beta-(1->2)-D-Man-alfa-(1->3)-D-Glc-beta-(1->4)-D-Glc-alfa-1-difosfo-ditrans,oktacis-undekaprenol
Ovaj enzim učestvuje u biosintezi eksopolisaharida ksantana.
Reference[uredi | uredi kod]
- ↑ Katzen, F., Ferreiro, D.U., Oddo, C.G., Ielmini, M.V., Becker, A., Puhler, A. and Ielpi, L. (1998). „Xanthomonas campestris' pv. campestris gum mutants: effects on xanthan biosynthesis and plant virulence”. J. Bacteriol. 180: 1607-1617. PMID 9537354.
- ↑ Ielpi, L., Couso, R.O. and Dankert, M.A. (1993). „Sequential assembly and polymerization of the polyprenol-linked pentasaccharide repeating unit of the xanthan polysaccharide in Xanthomonas campestris”. J. Bacteriol. 175: 2490-2500. PMID 7683019.
- ↑ Kim, S.Y., Kim, J.G., Lee, B.M. and Cho, J.Y. (2009). „Mutational analysis of the gum gene cluster required for xanthan biosynthesis in Xanthomonas oryzae' pv oryzae”. Biotechnol. Lett. 31: 265-270. PMID 18854951.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.