Galopamil

Galopamil
(IUPAC) ime
	(RS)-5-[2-(3,4-Dimetoksifenil)etil-metilamino]-2-propan-2-il-2-(3,4,5-trimetoksifenil)pentan nitril
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	16662-46-7
ATC kod	C08DA02
PubChem	1234
ChemSpider	1197
UNII	39WPC8JHR8
KEGG	D01969
ChEMBL	CHEMBL51149
Hemijski podaci
Formula	C28H40N2O5
Mol. masa	484,62 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C28H40N2O5/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5/h10-11,16-18,20H,9,12-15H2,1-8H3 ; Key: XQLWNAFCTODIRK-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Galopamil (INN) je L-tip blokatora kalcijumovog kanala. On je je analog verapamila. Galopamil se koristi za lečenje srčanih aritmija.^[6]^[7]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Sewing K-F, Hannemann H (1983). „Calcium Channel Antagonists Verapamil and Gallopamil Are Powerful Inhibitors of Acid Secretion in Isolated and Enriched Guinea Pig Parietal Cells”. Pharmacology 27: 9–14. DOI:10.1159/000137824.
↑ Mitić R., Biševac B., Stanojević Z., Bursać M., Đokić T. (2009). Efekt verapamila na trahealni odgovor izazvan histaminom i acetilholinom. 37. pp. 1-9. Arhivirano iz originala na datum 2011-05-31. Pristupljeno 2014-04-05.

Spoljašnje veze[uredi | uredi kod]

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Sewing K-F, Hannemann H (1983). „Calcium Channel Antagonists Verapamil and Gallopamil Are Powerful Inhibitors of Acid Secretion in Isolated and Enriched Guinea Pig Parietal Cells”. Pharmacology 27: 9–14. DOI:10.1159/000137824.

[7] Mitić R., Biševac B., Stanojević Z., Bursać M., Đokić T. (2009). Efekt verapamila na trahealni odgovor izazvan histaminom i acetilholinom. 37. pp. 1-9. Arhivirano iz originala na datum 2011-05-31. Pristupljeno 2014-04-05.

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Galopamil

Reference[uredi | uredi kod]

Spoljašnje veze[uredi | uredi kod]

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