Fosforibozilglicinamid formiltransferaza
(Preusmjereno sa stranice GAR transformilaza)
| Fosforibozilglicinamid formiltransferaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 2.1.2.2 | ||||||||
| CAS broj | 2604945 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fosforibozilglicinamid formiltransferaza (EC 2.1.2.2, 2-amino-N-ribozilacetamid 5'-fosfatna transformilaza, GAR formiltransferaza, GAR transformilaza, glicinamid ribonukleotidna transformilaza, GAR TFaza, 5,10-meteniltetrahidrofolat:2-amino-N-ribozilacetamid ribonukleotid transformilaza) je enzim sa sistematskim imenom 10-formiltetrahidrofolat:5'-fosforibozilglicinamid N-formiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 10-formiltetrahidrofolat + N1-(5-fosfo-D-ribozil)glicinamid tetrahidrofolat + N2-formil-N1-(5-fosfo-D-ribozil)glicinamid
Reference[uredi | uredi kod]
- ↑ Hartman, S.C. and Buchanan, J.M. (1959). „Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reaction”. J. Biol. Chem. 234: 1812-1816. PMID 13672969.
- ↑ Smith, G.K., Benkovic, P.A. and Benkovic, S.J. (1981). „L(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver”. Biochemistry 20: 4034-4036. PMID 7284307.
- ↑ Warren, L. and Buchanan, J.M. (1957). „Biosynthesis of the purines. XIX. 2-Amino-N-ribosylacetamide 5′-phosphate (glycinamide ribotide) transformylase”. J. Biol. Chem. 229: 613-626. PMID 13502326.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.