Fumarilacetoacetaza
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| Fumarilacetoacetaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 3.7.1.2 | ||||||||
| CAS broj | 9032-59-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fumarilacetoacetaza (EC 3.7.1.2, beta-diketonaza, fumarilacetoacetatna hidrolaza) je enzim sa sistematskim imenom 4-fumarilacetoacetat fumarilhidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-fumarilacetoacetat + H2O acetoacetat + fumarat
Ovaj enzim takođe deluje na druge 3,5- i 2,4-diokso kiseline.
Reference[uredi | uredi kod]
- ↑ Connors, W.M. and Stotz, E. (1949). „The purification and properties of a triacetic acid-hydrolyzing enzyme”. J. Biol. Chem. 178: 881-890. PMID 18117010.
- ↑ Edwards, S.W. and Knox, W.E. (1956). „Homogentisate metabolism: the isomerization of maleylacetoacetate by an enzyme which requires glutathione”. J. Biol. Chem. 220: 79-91. PMID 13319328.
- ↑ Meister, A. and Greenstein, J.P. (1948). „Enzymatic hydrolysis of 2,4-diketo acids”. J. Biol. Chem. 175: 573-588. PMID 18880754.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.