Fosfonopiruvatna hidrolaza

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Fosfonopiruvatna hidrolaza
Identifikatori
EC broj 3.11.1.3
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Fosfonopiruvatna hidrolaza (EC 3.11.1.3, PPH) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

3-fosfonopiruvat + H2O piruvat + fosfat

Ovaj enzim je visoko specifičan za fosfonopiruvatne supstrate.

Reference[uredi - уреди | uredi izvor]

  1. Ternan, N.G., Hamilton, J.T. and Quinn, J.P. (2000). "Initial in vitro characterisation of phosphonopyruvate hydrolase, a novel phosphate starvation-independent, carbon-phosphorus bond cleavage enzyme in Burkholderia cepacia Pal6". Arch. Microbiol. 173: 35–41. PMID 10648102. 
  2. Kulakova, A.N., Wisdom, G.B., Kulakov, L.A. and Quinn, J.P. (2003). "The purification and characterization of phosphonopyruvate hydrolase, a novel carbon-phosphorus bond cleavage enzyme from Variovorax sp. Pal2". J. Biol. Chem. 278: 23426–23431. PMID 12697754. 
  3. Chen, C.C., Han, Y., Niu, W., Kulakova, A.N., Howard, A., Quinn, J.P., Dunaway-Mariano, D. and Herzberg, O. (2006). "Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily". Biochemistry 45: 11491–11504. PMID 16981709. 

Literatura[uredi - уреди | uredi izvor]

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