Fosfonopiruvatna dekarboksilaza
(Preusmjereno sa stranice Fosfonopiruvat dekarboksilaza)
| Fosfonopiruvatna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.82 | ||||||||
| CAS broj | 151662-34-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fosfonopiruvatna dekarboksilaza (EC 4.1.1.82, 3-fosfonopiruvatna karboksilijaza) je enzim sa sistematskim imenom 3-fosfonopiruvat karboksilijaza (formira 2-fosfonoacetaldehid).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3-fosfonopiruvat 2-fosfonoacetaldehid + CO2
Ovaj enzim učestvuje u biosintezi 2-aminoetilfosfonata.
Reference[uredi | uredi kod]
- ↑ Zhang, G., Dai, J., Lu, Z. and Dunaway-Mariano, D. (2003). „The phosphonopyruvate decarboxylase from Bacteroides fragilis”. J. Biol. Chem. 278: 41302-41308. PMID 12904299.
- ↑ Seidel, H.M. and Knowles, J.R. (1994). „Interaction of inhibitors with phosphoenolpyruvate mutase: implications for the reaction mechanism and the nature of the active site”. Biochemistry 33: 5641-5646. PMID 8180189.
- ↑ Nakashita, H., Watanabe, K., Hara, O., Hidaka, T. and Seto, H. (1997). „Studies on the biosynthesis of bialaphos. Biochemical mechanism of C-P bond formation: discovery of phosphonopyruvate decarboxylase which catalyzes the formation of phosphonoacetaldehyde from phosphonopyruvate”. J. Antibiot. (Tokyo) 50: 212-219. PMID 9127192.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.