CDP-diacilglicerol—holin O-fosfatidiltransferaza
(Preusmjereno sa stranice Fosfatidilholin sintaza)
| CDP-diacilglicerol—holin O-fosfatidiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.8.24 | ||||||||
| CAS broj | 243666-86-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
CDP-diacilglicerol—holin O-fosfatidiltransferaza (EC 2.7.8.24, CDP-diglicerid-holin O-fosfatidiltransferaza) je enzim sa sistematskim imenom CDP-diacilglicerol:holin O-fosfatidiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CDP-diacilglicerol + holin CMP + fosfatidilholin
Za dejstvo ovog enzima je neophodan dvovalentni katjon Mn2+. Enzim funkcioniše u sa Mg2+.
Reference[uredi | uredi kod]
- ↑ de Rudder, K.E.E., Sohlenkamp, C. and Geiger, O. (1999). „Plant-exudated choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase”. J. Biol. Chem. 274: 20011-20016. PMID 10391951.
- ↑ Sohlenkamp, C., de Rudder, K.E.E., Röhrs, V., López-Lara, I.M. and Geiger, O. (2000). „Cloning and characterization of the gene for phosphatidylcholine synthase”. J. Biol. Chem. 275: 18919-18925. PMID 10858449.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.