Flukonazol

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Flukonazol
(IUPAC) ime
2-(2,4-difluorofenil)-1,3-bis(1H-1,2,4-triazol-1-il)propan-2-ol
Klinički podaci
Robne marke Biocanol, Biozolene, Diflucan, Elazor
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 86386-73-4
ATC kod D01AC15 , J02AC01
PubChem[1][2] 3365
DrugBank DB00196
ChemSpider[3] 3248
ChEMBL[4] CHEMBL46081 YesY
Hemijski podaci
Formula C13H12F2N6O 
Mol. masa 306.2708
SMILES eMolekuli & PubHem
Fizički podaci
Tačka topljenja 138-140 °C (-82 °F)
Farmakokinetički podaci
Poluvreme eliminacije 30 sati
Izlučivanje 80% urinom
Farmakoinformacioni podaci
Trudnoća ?
Pravni status
Način primene Oralno; Intravenozno

Flukonazol je triazolni antifungalni agens koji se koristi za tretman Oropharyngeal candidiasis i Cryptococcal meningitis kod obolelih od side.[5][6]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  5. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). "DrugBank 3.0: a comprehensive resource for omics research on drugs". Nucleic Acids Res. 39 (Database issue): D1035–41. PMID 21059682. 
  6. Nucleic Acids Res (2008). "DrugBank: a knowledgebase for drugs, drug actions and drug targets" 36 (Database issue). pp. D901–6. PMID 18048412. 

Spoljašnje veze[uredi - уреди | uredi izvor]

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