Feredoksin:protohlorofilid reduktaza (ATP-zavisna)
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| Feredoksin:protohlorofilid reduktaza (ATP-zavisna) | |||||||||
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| Identifikatori | |||||||||
| EC broj | 1.3.7.7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Feredoksin:protohlorofilid reduktaza (ATP-zavisna) (EC 1.3.7.7, protohlorofillidna reduktaza nezavisna od svetla) je enzim sa sistematskim imenom ATP-zavisni feredoksin:protohlorofilid-a 7,8-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hlorofilid a + redukovani feredoksin + 2 ATP protohlorofilid + oksidovani feredoksin + 2 ADP + 2 fosfat
Ova reakcija se odvija kod fotosintetičkih bakterija, cijanobakterija, zelenih algi i gimnosperma. Enzim katalizuje trans-redukciju D-prstena protohlorofilida. Produkt ima (7S,8S)-konfiguraciju.
Reference[uredi | uredi kod]
- ↑ Fujita, Y., Matsumoto, H., Takahashi, Y. and Matsubara, H. (1993). „Identification of a nifDK-like gene (ORF467) involved in the biosynthesis of chlorophyll in the cyanobacterium Plectonema boryanum”. Plant Cell Physiol. 34: 305-314. PMID 8199775.
- ↑ Nomata, J., Ogawa, T., Kitashima, M., Inoue, K. and Fujita, Y. (2008). „NB-protein (BchN-BchB) of dark-operative protochlorophyllide reductase is the catalytic component containing oxygen-tolerant Fe-S clusters”. FEBS Lett. 582: 1346-1350. PMID 18358835.
- ↑ Muraki, N., Nomata, J., Ebata, K., Mizoguchi, T., Shiba, T., Tamiaki, H., Kurisu, G. and Fujita, Y. (2010). „X-ray crystal structure of the light-independent protochlorophyllide reductase”. Nature 465: 110-114. PMID 20400946.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.