Fenilacetaldoksimska dehidrataza
(Preusmjereno sa stranice Fenilacetaldoksim dehidrataza)
| Fenilacetaldoksimska dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.99.1.7 | ||||||||
| CAS broj | 203210-76-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fenilacetaldoksimska dehidrataza (EC 4.99.1.7, PAOx dehidrataza, arilacetaldoksimska dehidrataza, OxdB, (Z)-fenilacetaldehid-oksimska hidrolijaza) je enzim sa sistematskim imenom (Z)-fenilacetaldehid-oksim hidrolijaza (formira fenilacetonitril).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (Z)-fenilacetaldehid oksim fenilacetonitril + H2O
Enzim iz Bacillus sp. OxB-1 sadrži protohem IX.
Reference[uredi | uredi kod]
- ↑ Kato, Y., Nakamura, K., Sakiyama, H., Mayhew, S.G. and Asano, Y. (2000). „Novel heme-containing lyase, phenylacetaldoxime dehydratase from Bacillus sp. strain OxB-1: purification, characterization, and molecular cloning of the gene”. Biochemistry 39: 800-809. PMID 10651646.
- ↑ Kobayashi, K., Yoshioka, S., Kato, Y., Asano, Y. and Aono, S. (2005). „Regulation of aldoxime dehydratase activity by redox-dependent change in the coordination structure of the aldoxime-heme complex”. J. Biol. Chem. 280: 5486-5490. PMID 15596434.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.