FMN adenililtransferaza
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| FMN adenililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.2 | ||||||||
| CAS broj | 9026-37-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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FMN adenililtransferaza (EC 2.7.7.2, FAD pirofosforilaza, riboflavin mononukleotid adenililtransferaza, adenozin trifosfat-riboflavin mononukleotid transadenilaza, adenozin trifosfat-riboflavin mononukleotid transadenilaza, riboflavin adenin dinukleotid pirofosforilaza, riboflavin adenin dinukleotid adenililtransferaza, flavin adenin dinukleotid sintetaza, FADS) je enzim sa sistematskim imenom ATP:FMN adenililtransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Za rad ovog enzima je neophodan jon Mg2+. On je visoko specifičan za ATP kao donor fosfata.
Reference[uredi | uredi kod]
- ↑ Giri, K.V., Rao, N.A., Cama, H.R. and Kumar, S.A. (1960). „Studies on flavinadenine dinucleotide-synthesizing enzyme in plants”. Biochem. J. 75: 381-386. PMID 13828163.
- ↑ Schrecker, A.W. and Kornberg, A. (1950). „Reversible enzymatic synthesis of flavin-adenine dinucleotide”. J. Biol. Chem. 182: 795-803.
- ↑ Sandoval, F.J. and Roje, S. (2005). „An FMN hydrolase is fused to a riboflavin kinase homolog in plants”. J. Biol. Chem. 280: 38337-38345. PMID 16183635.
- ↑ Oka, M. and McCormick, D.B. (1987). „Complete purification and general characterization of FAD synthetase from rat liver”. J. Biol. Chem. 262: 7418-7422. PMID 3034893.
- ↑ Brizio, C., Galluccio, M., Wait, R., Torchetti, E.M., Bafunno, V., Accardi, R., Gianazza, E., Indiveri, C. and Barile, M. (2006). „Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase”. Biochem. Biophys. Res. Commun. 344: 1008-1016. PMID 16643857.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.