Etanolamin-fosfatna fosfo-lijaza
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| Etanolamin-fosfatna fosfo-lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.2 | ||||||||
| CAS broj | 37290-88-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Etanolamin-fosfatna fosfo-lijaza (EC 4.2.3.2, O-fosfoetanolamin-fosfolijaza, amino alkohol O-fosfat fosfolijaza, O-fosforiletanol-amin fosfo-lijaza, etanolamin-fosfat fosfo-lijaza (deaminacija)) je enzim sa sistematskim imenom etanolamin-fosfat fosfat-lijaza (deaminacija, formira acetaldehid).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- etanolamin fosfat + H2O acetaldehid + NH3 + fosfat
Ovaj enzim je piridoksal-fosfatni protein.
Reference[uredi | uredi kod]
- ↑ Fleshood, H.L. and Pitot, H.C. (1970). „The metabolism of O-phosphorylethanolamine in animal tissues. I. O-Phosphorylethanolamine phospho-lyase: partial purification and characterization”. J. Biol. Chem. 245: 4414-4420. PMID 5498429.
- ↑ Jones, A., Faulkner, A. and Turner, J.M. (1973). „Microbial metabolism of amino alcohols. Metabolism of ethanolamine and 1-aminopropan-2-ol in species of Erwinia and the roles of amino alcohol kinase and amino alcohol o-phosphate phospho-lyase in aldehyde formation”. Biochem. J. 134: 959-968. PMID 4357716.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.