Eksoribonukleaza II

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Eksoribonukleaza II
Identifikatori
EC broj 3.1.13.1
CAS broj 37288-24-7
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Eksoribonukleaza II (EC 3.1.13.1, ribonukleaza II, ribonukleaza Q, BN ribonukleaza, Escherichia coli ekso-RNaza II, RNaza II, eksoribonukleaza, 5'-eksoribonukleaza) je enzim sa sistematskim imenom '.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Eksonukleolitičko razlaganje u 3'- ka 5'- smeru čime se formiraju nukleozid 5'-fosfati

Ova enzim preferentno deluje na jednolačanu DNK.

Reference[uredi - уреди | uredi izvor]

  1. Nossal, N.G. and Singer, M. (1968). "The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II". J. Biol. Chem. 243: 913–922. PMID 4867942. 
  2. Schmidt, F.J. and McClain, W.H. (1978). "An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA". Nucleic Acids Res. 5: 4129–4139. PMID 364422. 
  3. Shimura, Y., Sakano, H. and Nagawa, F. (1978). "Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties". Eur. J. Biochem. 86: 267–281. PMID 350582. 
  4. Sporn, M.B., Lazarus, H.M. Smith, J.M. and Henderson, W.R. (1969). "Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse". Biochemistry 8: 1698–1706. PMID 5805304. 

Literatura[uredi - уреди | uredi izvor]

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