Piknoporopepsin
(Preusmjereno sa stranice EC 3.4.23.30)
| Piknoporopepsin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.30 | ||||||||
| CAS broj | 77967-78-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Piknoporopepsin (EC 3.4.23.30, proteinaza Ia, Pycnoporus coccineus aspartinska proteinaza, Trametes kiselinskaa proteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Slična specifičnost sa pepsinom A, mada uža. Odavajaju se samo tri veze u B lancu insulina: Ala14-Leu, Tyr16-Leu, i Phe24-Phe
Ovaj enzim je prisutan in bazidiomiceti Pycnoporus sanguineus .
Reference[uredi | uredi kod]
- ↑ Tomoda, K. and Shimazono, H. (1964). „Acid protease produced by Trametes sanguinea a wood-destroying fungus. Part I. Purification and crystallization of the enzyme”. Agric. Biol. Chem. 28: 770-773.
- ↑ Tsuru, D., Hattori, A., Tsuji, H., Yamamoto, T. and Fukumoto, J. (1969). „Studies on mold proteases. Part II. Substrate specificity of acid protease of Rhizopus chinensis”. Agric. Biol. Chem. 33: 1419-1426.
- ↑ Ichishima, E., Kumagai, H. and Tomoda, K. (1980). „Substrate specificity of carboxyl proteinase from Pycnoporus coccineus, a wood-deteriorating fungus”. Curr. Microbiol. 3: 333-337.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.