2'-Hidroksibifenil-2-sulfinatna desulfinaza
(Preusmjereno sa stranice EC 3.13.1.3)
| 2'-Hidroksibifenil-2-sulfinatna desulfinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.13.1.3 | ||||||||
| CAS broj | 198154-06-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2'-Hidroksibifenil-2-sulfinatna desulfinaza (EC 3.13.1.3, hidrolaza kodirana dszB genom, 2-(2-hidroksifenil) benzensulfinat:H2O hidrolaza, DszB, HBPSi desulfinaza, 2-(2-hidroksifenil) benzensulfinatna sulfohidrolaza, HPBS desulfinaza, 2-(2-hidroksifenil)benzensulfinatna hidrolaza, 2-(2'-hidroksifenil)benzensulfinatna desulfinaza, 2-(2-hidroksifenil)benzensulfinatna desulfinaza) je enzim sa sistematskim imenom 2'-hidroksibifenil-2-sulfinat sulfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2'-hidroksibifenil-2-sulfinat + H2O 2-hidroksibifenil + sulfit
Enzim iz Rhodococcus vrste IGTS8 je kodiran plazmidom koji sadrži dibenzotiofen-desumporizacioni (dsz) operon.
Reference[uredi | uredi kod]
- ↑ Oldfield, C., Pogrebinsky, O., Simmonds, J., Ölson, E.S. and Kulpa, C.F. (1997). „Elucidation of the metabolic pathway for dibenzothiophene desulfurization by Rhodococcus sp. strain IGTS8 (ATCC 53968)”. Microbiology 143: 2961-2973. PMID 9308179.
- ↑ Nakayama, N., Matsubara, T., Ohshiro, T., Moroto, Y., Kawata, Y., Koizumi, K., Hirakawa, Y., Suzuki, M., Maruhashi, K., Izumi, Y. and Kurane, R. (2002). „A novel enzyme, 2′-hydroxybiphenyl-2-sulfinate desulfinase (DszB), from a dibenzothiophene-desulfurizing bacterium Rhodococcus erythropolis KA2-5-1: gene overexpression and enzyme characterization”. Biochim. Biophys. Acta 1598: 122-130. PMID 12147352.
- ↑ Watkins, L.M., Rodriguez, R., Schneider, D., Broderick, R., Cruz, M., Chambers, R., Ruckman, E., Cody, M. and Mrachko, G.T. (2003). „Purification and characterization of the aromatic desulfinase, 2-(2′-hydroxyphenyl)benzenesulfinate desulfinase”. Arch. Biochem. Biophys. 415: 14-23. PMID 12801508.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.