Ribonukleaza T2
(Preusmjereno sa stranice EC 3.1.27.1)
| Ribonukleaza T2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.27.1 | ||||||||
| CAS broj | 37278-25-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ribonukleaza T2 (EC 3.1.27.1, ribonukleaza II, bazno nespecifična ribonukleaza, RNaza (bazno nespecifična), ribonukleaza bez bazne specifičnosti, nespecifična RNaza, RNaza Ms, RNaza M, RNaza II, Escherichia coli ribonukleaza II, ribonukleat nukleotido-2'-transferaza (ciklizacija), kiselinska ribonukleaza, RNKaza CL, Escherichia coli ribonukleaza I' ribonukleaza PP2, ribonukleaza N2, ribonukleaza M, kiselinska RNaza, ribonukleaza (bazno nespecifična), ribonukleaza (bazno nespecifična), RNaza T2, ribonukleaza PP3, ribonukleat 3'-oligonukleotidna hidrolaza, RNaza II, ribonukleaza U4) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Dvostepeno endonukleolitičko razlaganje do nukleozid 3'-fosfata i 3'-fosfooligonukleotida sa 2',3'-cikličnim fosfatnim intermedijerima
Reference[uredi | uredi kod]
- ↑ Garcia-Segura, J.M., Orozco, M.M., Fominaya, J.M. and Gavilanes, J.G. (1986). „Purification, molecular and enzymic characterization of an acid RNase from the insect Ceratitis capitata”. Eur. J. Biochem. 158: 367-372. PMID 3732273.
- ↑ Heppel, L.A. (1966). „Pig liver nuclei ribonuclease”. u: Cantoni, G.L. and Davies, D.R.. Procedures in Nucleic Acid Research. New York: Procedures in Nucleic Acid Research. str. 31-36.
- ↑ Reddi, K.K. and Mauser, L.J. (1965). „Studies on the formation of tobacco mosaic virus ribonucleic acid. VI. Mode of degradation of host ribonucleic acid to ribonucleosides and their conversion to ribonucleoside 5′-phosphates”. Proc. Natl. Acad. Sci. USA 53: 607-613. PMID 14338240.
- ↑ Uchida, I. and Egami, F. (1967). „The specificity of ribonuclease T2”. J. Biochem. (Tokyo) 61: 44-53. PMID 6048969.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Heppel, L.A. (1966). „Pig liver nuclei ribonuclease”. u: Cantoni, G.L. and Davies, D.R.. Procedures in Nucleic Acid Research. New York: Procedures in Nucleic Acid Research. str. 31-36.