Difosfat-purin nukleozid kinaza
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| Difosfat-purin nukleozid kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.143 | ||||||||
| CAS broj | 70356-41-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Difosfat-purin nukleozid kinaza (EC 2.7.1.143, pirofosfat-purin nukleozidna kinaza) je enzim sa sistematskim imenom difosfat:purin nukleozid fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Enzim iz Acholeplasma klase Mollicutes katalizuje konverziju adenozina, guanozina i inozina u AMP, GMP i IMP. ATP ne može da zameni difosfat kao supstrat.
Reference[uredi | uredi kod]
- ↑ Tryon, V.V., Pollack, D. (1984). „Purine metabolism in Acholeplasma laidlawii B: novel PPi-dependent nucleoside kinase activity”. J. Bacteriol. 159: 265-270. PMID 6330034.
- ↑ Tryon, V.V., Pollack, J.D. (1985). „Distinctions in Mollicutes purine metabolism: pyrophosphate-dependent nucleoside kinase and dependence on guanylate salvage”. Int. J. Systematic Bacteriol. 35: 497-501.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.