Diacilglicerol kinaza (CTP zavisna)
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| Diacilglicerol kinaza (CTP zavisni) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.174 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Diacilglicerol kinaza (CTP zavisni) (EC 2.7.1.174, DAG kinaza, CTP-zavisna diacilglicerolna kinaza, digliceridna kinaza) je enzim sa sistematskim imenom CTP:1,2-diacil-sn-glicerol 3-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CTP + 1,2-diacil-sn-glicerol CDP + 1,2-diacil-sn-glicerol 3-fosfat
Za rad ovog enzima je neophodan Ca2+ ili Mg2+.
Reference[uredi | uredi kod]
- ↑ Han, G.S., O'Hara, L., Carman, G.M. and Siniossoglou, S. (2008). „An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth”. J. Biol. Chem. 283: 20433-20442. PMID 18458075.
- ↑ Han, G.S., O'Hara, L., Siniossoglou, S. and Carman, G.M. (2008). „Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase”. J. Biol. Chem. 283: 20443-20453. PMID 18458076.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.