Diacilglicerol holinfosfotransferaza
| Diacilglicerol holinfosfotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.8.2 | ||||||||
| CAS broj | 9026-13-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Diacilglicerol holinfosfotransferaza (EC 2.7.8.2, fosforilholin-gliceridna transferaza, alkilacilglicerol holinfosfotransferaza, 1-alkil-2-acetilglicerol holinfosfotransferaza, holinfosfotransferaza, CPT, alkilacilglicerol holin fosfotransferaza, diacilglicerol holin fosfotransferaza, 1-alkil-2-acetil-m-glicerol:CDPholin holin fosfotransferaza, CDP-holin digliceridna fosfotransferaza, citidin difosfoholin gliceridna transferaza, citidin difosforilholin diglicerid transferaza, fosfoholin diacilgliceroltransferaza, sn-1,2-diacilglicerol holinfosfotransferaza, 1-alkil-2-acetil-sn-glicerol holinfosfotransferaza, CDP holin:1,2-diacilglicerol holinfosfotransferaza, CDP-holin:1,2-diacilglicerol holinfosfotransferaza) je enzim sa sistematskim imenom CDP-holin:1,2-diacil-sn-glicerol holinfosfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CDP-holin + 1,2-diacil-sn-glicerol CMP + fosfatidilholin
1-Alkil-2-acilglicerol može da deluje kao akceptor.
Reference[uredi | uredi kod]
- ↑ Coleman, R. and Bell, R.M. (1977). „Phospholipid synthesis in isolated fat cells. Studies of microsomal diacylglycerol cholinephosphotransferase and diacylglycerol ethanolaminephosphotransferase activities”. J. Biol. Chem. 252: 3050-3056. PMID 192727.
- ↑ Lee, T.-C., Blank, M.L., Fitzgerald, V. and Snyder, F. (1982). „Formation of alkylacyl- and diacylglycerophosphocholines via diradylglycerol cholinephosphotransferase in rat liver”. Biochim. Biophys. Acta 713: 479-483. PMID 6295501.
- ↑ Parsasarathy, S., Cady, R.K., Kraushaar, D.S., Sladek, N.E. and Baumann, W.J. (1978). „Inhibition of diacylglycerol:CDPcholine cholinephosphotransferase activity by dimethylaminoethyl p-chlorophenoxyacetate”. Lipids 13: 161-164. PMID 204847.
- ↑ Renooij, W. and Snyder, F. (1981). „Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor and a hypotensive lipid) by cholinephosphotransferase in various rat tissues”. Biochim. Biophys. Acta 663: 545-556. PMID 6260215.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.