Dezoksiribonukleaza IV (fag-T4-indukovana)
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| Dezoksiribonukleaza IV (fag-T4-indukovana) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.21.2 | ||||||||
| CAS broj | 63363-78-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dezoksiribonukleaza IV (fag-T4-indukovana) (EC 3.1.21.2, endodezoksiribonukleaza IV (fagom T4-indukovana), E. coli endonukleaza IV, endodezoksiribonukleaza, redoksiendonukleaza, deoksiriboendonukleaza, Escherichia coli endonukleaza II, endonukleaza II, DNK-adenin-transferaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endonukleolitičko razlaganje do 5'-fosfooligonukleotidnih krajnjih produkata
Ovaj enzim preferentno deluje na jednolančanu DNK.
Reference[uredi | uredi kod]
- ↑ Friedberg, E.C. and Goldthwait, D.A. (1969). „Endonuclease II of E. coli. I. Isolation and purification”. Proc. Natl. Acad. Sci. USA 62: 934-940. PMID 4895219.
- ↑ Friedberg, E.C., Hadi, S.-M. and Goldthwait, D.A. (1969). „Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid”. J. Biol. Chem. 244: 5879-5889. PMID 4981786.
- ↑ Hadi, S.M. and Goldthwait, D.A. (1971). „Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid”. Biochemistry 10: 4986-4993. PMID 4944066.
- ↑ Sadowski, P.D. and Hurwitz, J. (1969). „Enzymatic breakage of deoxyribonucleic acid. I. Purification and properties of endonuclease II from T4 phage-infected Escherichia coli”. J. Biol. Chem. 244: 6182-6191. PMID 4310836.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.