D-sedoheptuloza 7-fosfatna izomeraza
(Preusmjereno sa stranice D-sedoheptuloza 7-fosfat izomeraza)
| D-sedoheptuloza 7-fosfatna izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.3.1.28 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
D-sedoheptuloza 7-fosfatna izomeraza (EC 5.3.1.28, sedoheptuloza-7-fosfat izomeraza, fosfoheptoza izomeraza, gmhA (gen), lpcA (gen)) je enzim sa sistematskim imenom D-glicero-D-mano-heptoza 7-fosfat aldoza-ketoza-izomeraza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-sedoheptuloza 7-fosfat D-glicero-D-mano-heptoza 7-fosfat
Kod Gram-negativih bakterija ovaj enzim učestvuje u biosintezi ADP-L-glicero-beta-D-mano-heptoze.
Reference[uredi | uredi kod]
- ↑ Kneidinger, B., Marolda, C., Graninger, M., Zamyatina, A., McArthur, F., Kosma, P., Valvano, M.A. and Messner, P. (2002). „Biosynthesis pathway of ADP-L-glycero-β-D-manno-heptose in Escherichia coli”. J. Bacteriol. 184: 363-369. PMID 11751812.
- ↑ Kneidinger, B., Graninger, M., Puchberger, M., Kosma, P. and Messner, P. (2001). „Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose”. J. Biol. Chem. 276: 20935-20944. PMID 11279237.
- ↑ Valvano, M.A., Messner, P. and Kosma, P. (2002). „Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides”. Microbiology 148: 1979-1989. PMID 12101286.
- ↑ Kim, M.S. and Shin, D.H. (2009). „A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei”. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65: 1110-1112. PMID 19923728.
- ↑ Taylor, P.L., Blakely, K.M., de Leon, G.P., Walker, J.R., McArthur, F., Evdokimova, E., Zhang, K., Valvano, M.A., Wright, G.D. and Junop, M.S. (2008). „Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants”. J. Biol. Chem. 283: 2835-2845. PMID 18056714.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.