Cijanoalaninska nitrilaza
(Preusmjereno sa stranice Cijanoalanin nitrilaza)
| Cijanoalaninska nitrilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.5.4 | ||||||||
| CAS broj | 85638-44-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Cijanoalaninska nitrilaza (EC 3.5.5.4, beta-cijanoalaninska nitrilaza) je enzim sa sistematskim imenom 3-cijano-L-alanin aminohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3-cijano-L-alanin + 2H2O L-aspartat + NH3 (sveukupna reakcija)
- (1a) 3-cijano-L-alanin +H2O L-asparagin
- (1b) L-asparagin +H2O L-aspartat + NH3
L-asparagin se formira kao intermedijer.
Reference[uredi | uredi kod]
- ↑ Yanase, H., Sakai, T. and Tonomuro, K. (1983). „Purification, crystallization and some properties of β-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13”. Agric. Biol. Chem. 47: 473-482.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.