Cijanatna hidrataza

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Cijanatna hidrataza
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Identifikatori
EC broj 4.2.1.104
CAS broj 37289-24-0
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Cijanatna hidrataza (EC 4.2.1.104, cijanatna lijaza, cijanatna hidrolaza, cijanatna aminohidrolaza, cijanatna C-N-lijaza) je enzim sa sistematskim imenom karbamat hidrolijaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju

cijanat + HCO3- + 2 H+ NH3 + 2 CO2 (sveukupna reakcija)
(1a) cijanat + HCO3- + H+ karbamat + CO2
(1b) karbamat + H+ NH3 + CO2 (spontana reakcija)

Ovaj enzim, koji je pristuan u bakterijama i biljkama, posreduje razlaganje cijanata.

Reference[uredi - уреди | uredi izvor]

  1. Anderson, P.M. (1980). "Purification and properties of the inducible enzyme cyanase". Biochemistry 19: 2882–2888. PMID 6994799. 
  2. Johnson, W.V. and Anderson, P.M. (1987). "Bicarbonate is a recycling substrate for cyanase". J. Biol. Chem. 262: 9021–9025. PMID 3110153. 
  3. Taussig, A. (1960). "T'he synthesis of the induced enzyme, "cyanase", in E. coli". Biochim. Biophys. Acta 44: 510–519. PMID 13775509. 
  4. Taussig, A. (1965). "Some properties of the induced enzyme cyanase". Can. J. Biochem. 43: 1063–1069. PMID 5322950. 
  5. Anderson, P.M., Korte, J.J. and Holcomb, T.A. (1994). "Reaction of the N-terminal methionine residues in cyanase with diethylpyrocarbonate". Biochemistry 33: 14121–14125. PMID 7947823. 
  6. Kozliak, E.I., Fuchs, J.A., Guilloton, M.B. and Anderson, P.M. (1995). "Role of bicarbonate/CO2 in the inhibition of Escherichia coli growth by cyanate". J. Bacteriol. 177: 3213–3219. PMID 7768821. 
  7. Walsh, M.A., Otwinowski, Z., Perrakis, A., Anderson, P.M. and Joachimiak, A. (2000). "Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site". Structure 8: 505–514. PMID 10801492. 

Literatura[uredi - уреди | uredi izvor]

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