Blasticidin S deaminaza
(Preusmjereno sa stranice Blasticidin-S deaminaza)
Blasticidin S deaminaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.5.4.23 | ||||||||
CAS broj | 54576-55-5 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Blasticidin S deaminaza (EC 3.5.4.23) je enzim sa sistematskim imenom blasticidin-S aminohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- blasticidin S + H2O deaminohidroksiblasticidin S + NH3
Ovaj enzim katalizuje deaminaciju citozinske grupe antibiotika blasticidin Sa, citomicin i acetilblasticidin S.
Reference[uredi | uredi kod]
- ↑ Yamaguchi, I., Shibata, H., Seto, H. and Misato, T. (1975). „Isolation and purification of blasticidin S deaminase from Aspergillus terreus”. J. Antibiot. 28: 7-14. PMID 236272.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.