Aspartatna 4-dekarboksilaza
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| Aspartatna 4-dekarboksilaza | |||||||||
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| Aspartatna 4-dekarboksilaza dodekamer, Comamonas testosteroni | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.1.1.12 | ||||||||
| CAS broj | 9024-57-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Aspartatna 4-dekarboksilaza (EC 4.1.1.12, desulfinaza, aminomalonska dekarboksilaza, aspartatna beta-dekarboksilaza, aspartatna omega-dekarboksilaza, aspartinska omega-dekarboksilaza, aspartinska beta-dekarboksilaza, L-aspartatna beta-dekarboksilaza, cistein sulfinska desulfinaza, L-cistein sulfinatno kiselinska desulfinaza, L-aspartatna 4-karboksi-lijaza) je enzim sa sistematskim imenom L-aspartat 4-karboksi-lijaza (formira L-alanin).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-aspartat L-alanin + CO2
Ovaj enzim je piridoksal-fosfatni protein.
Reference[uredi | uredi kod]
- ↑ Kakimoto, T., Kato, J., Shibitani, T., Nishimura, N. and Chibata, I. (1969). „Crystalline L-aspartate β-decarboxylase of Pseudomonas dacunhae. I. Crystallization and some physiocochemical properties”. J. Biol. Chem. 244: 353-358. PMID 5773301.
- ↑ Novogrodsky, A. and Meister, A. (1964). „Control of aspartate β-decarboxylase activity by transamination”. J. Biol. Chem. 239: 879-888. PMID 14154469.
- ↑ Palekar, A.G., Tate, S.S. and Meister, A. (1970). „Inhibition of aspartate β-decarboxylase by aminomalonate. Stereospecific decarboxylation of aminomalonate to glycine”. Biochemistry 9: 2310-2315. PMID 5424207.
- ↑ Wilson, E.M. and Kornberg, H.L. (1963). „Properties of crystalline L-aspartate 4-carboxy-lyase from Achromobacter sp”. Biochem. J. 88: 578-587. PMID 14071532.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.