Arogenat dehidrogenaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Arogenat dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.43 | ||||||||
| CAS broj | 64295-75-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Arogenat dehidrogenaza (EC 1.3.1.43, arogena dehidrogenaza (nespedifična), cikloheksadienilna dehidrogenaza, pretirozinska dehidrogenaza (nespecifična), L-arogenat:NAD+ oksidoreduktaza) je enzim sa sistematskim imenom L-arogenat:NAD+ oksidoreduktaza (dekarboksilacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-arogenat + NAD+ L-tirozin + NADH + CO2
Reference[uredi | uredi kod]
- ↑ Stenmark, S.L., Pierson, D.L., Jensen, R.A. and Glover, G.I. (1974). „Blue-green bacteria synthesise L-tyrosine by the pretyrosine pathway”. Nature 247: 290-292. PMID 4206476.
- ↑ Byng, G., Whitaker, R., Flick, C. and Jensen, R.A. (1981). „Enzymology of L-tyrosine biosynthesis in corn (Zea mays)”. Phytochemistry 20: 1289-1292.
- ↑ Mayer, E., Waldner-Sander, S., Keller, B., Keller, E. and Lingens, F. (1985). „Purification of arogenate dehydrogenase from Phenylobacterium immobile”. FEBS Lett. 179: 208-212. PMID 3967752.
- ↑ Lingens, F., Keller, E. and Keller, B. (1987). „Arogenate dehydrogenase from Phenylobacterium immobile”. Methods Enzymol. 142: 513-518.
- ↑ Zamir, L.O., Tiberio, R., Devor, K.A., Sauriol, F., Ahmad, S. and Jensen, R.A. (1988). „Structure of D-prephenyllactate. A carboxycyclohexadienyl metabolite from Neurospora crassa”. J. Biol. Chem. 263: 17284-17290. PMID 2972718.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vidi još[uredi | uredi kod]
- EC 1.3.1.12, prefenat dehidrogenaza
- EC 1.3.1.78, arogenat dehidrogenaza (NADP+)
- EC 1.3.1.79, arogenat dehidrogenaza (NAD(P)+)