Antranilat 3-monooksigenaza
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| Antranilat 3-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.16.3 | ||||||||
| CAS broj | 37256-79-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Antranilat 3-monooksigenaza (EC 1.14.16.3, antranilatna 3-hidroksilaza, antranilatna hidroksilaza, antranilna hidroksilaza, antranilno kiselinska hidroksilaza) je enzim sa sistematskim imenom antranilat,tetrahidrobiopterin:kiseonik oksidoreduktaza (3-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- antranilat + tetrahidrobiopterin + O2 3-hidroksiantranilat + dihidrobiopterin + H2O
Za rad ovog enzima je neophodan jon Fe2+.
Reference[uredi | uredi kod]
- ↑ Jequier, E., Robinson, B.S., Lovenberg, W. and Sjoerdsma, A. (1969). „Further studies on tryptophan hydroxylase in rat brainstem and beef pineal”. Biochem. Pharmacol. 18: 1071-1081. PMID 5789774.
- ↑ Nair, P.M. and Vaidyanathan, C.S. (1965). „Anthranilic acid hydroxylase from Tecoma stans”. Biochim. Biophys. Acta 110: 521-531.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.