Amidofosforiboziltransferaza
| Amidofosforiboziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Amidofosforiboziltransferaza tetramer, E.Coli | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.4.2.14 | ||||||||
| CAS broj | 9031-82-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Amidofosforiboziltransferaza (EC 2.4.2.14, fosforibozildifosfat 5-amidotransferaza, glutamin fosforibozildifosfat amidotransferaza, alfa-5-fosforibozil-1-pirofosfat amidotransferaza, 5'-fosforibozilpirofosfat amidotransferaza, 5-fosforibozil-1-pirofosfat amidotransferaza, 5-fosfororibozil-1-pirofosfat amidotransferaza, glutamin 5-fosforibozilpirofosfat amidotransferaza, glutamin ribozilpirofosfat 5-fosfat amidotransferaza, fosforiboza pirofosfat amidotransferaza, fosforibozil pirofosfat amidotransferaza, fosforibozilpirofosfat glutamil amidotransferaza, 5-fosforibozilamin:difosfat fosfo-alfa-D-riboziltransferaza (glutamatna amidacija)) je enzim sa sistematskim imenom 5-fosfo-beta-D-ribozilamin:difosfat fosfo-alfa-D-riboziltransferaza (glutamatna amidacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 5-fosfo-beta-D-ribozilamin + difosfat + L-glutamat L-glutamin + 5-fosfo-alfa-D-riboza 1-difosfat +H2O
- ↑ Caskey, C.T., Ashton, D.M. and Wyngaarden, J.B. (1964). „The enzymology of feedback inhibition of glutamine phosphoribosylpyrophosphate amidotransferase by purine ribonucleotides”. J. Biol. Chem. 239: 2570-2579. PMID 14235537.
- ↑ Hartman, S.C. and Buchanan, J.M. (1958). „Biosynthesis of the purines. XXI. 5-Phosphoribosylpyrophosphate amidotransferase”. J. Biol. Chem. 233: 451-455. PMID 13563519.
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