Alkohol dehidrogenaza (hinon)
Prijeđi na navigaciju
Prijeđi na pretragu
| Alkohol dehidrogenaza (hinon) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.5.5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Alkohol dehidrogenaza (hinon) (EC 1.1.5.5, tip III ADH, membranska hinohemoproteinska alkoholna dehidrogenaza) je enzim sa sistematskim imenom alkohol:hinon oksidoreduktaza.[1][2][3][4][5][6][7][8][9] Ovaj enzim katalizuje sledeću hemijsku reakciju
- etanol+ ubihinon acetaldehid + ubihinol
Ovaj enzim je prisutan kod bakterija sirćetne kiseline, kod kojih učestvuje u formiranju kiseline.
Reference[uredi | uredi kod]
- ↑ Gomez-Manzo, S., Contreras-Zentella, M., Gonzalez-Valdez, A., Sosa-Torres, M., Arreguin-Espinoza, R. and Escamilla-Marvan, E. (2008). „The PQQ-alcohol dehydrogenase of Gluconacetobacter diazotrophicus”. Int. J. Food Microbiol. 125: 71-78. PMID 18321602.
- ↑ Shinagawa, E., Toyama, H., Matsushita, K., Tuitemwong, P., Theeragool, G. and Adachi, O. (2006). „A novel type of formaldehyde-oxidizing enzyme from the membrane of Acetobacter sp. SKU 14”. Biosci. Biotechnol. Biochem. 70: 850-857. PMID 16636451.
- ↑ Chinnawirotpisan, P., Theeragool, G., Limtong, S., Toyama, H., Adachi, O.O. and Matsushita, K. (2003). „Quinoprotein alcohol dehydrogenase is involved in catabolic acetate production, while NAD-dependent alcohol dehydrogenase in ethanol assimilation in Acetobacter pasteurianus SKU1108”. J. Biosci. Bioeng. 96: 564-571. PMID 16233574.
- ↑ Frebortova, J., Matsushita, K., Arata, H. and Adachi, O. (1998). „Intramolecular electron transport in quinoprotein alcohol dehydrogenase of Acetobacter methanolicus: a redox-titration stud”. Biochim. Biophys. Acta 1363: 24-34. PMID 9526036.
- ↑ Matsushita, K., Kobayashi, Y., Mizuguchi, M., Toyama, H., Adachi, O., Sakamoto, K. and Miyoshi, H. (2008). „A tightly bound quinone functions in the ubiquinone reaction sites of quinoprotein alcohol dehydrogenase of an acetic acid bacterium, Gluconobacter suboxydans”. Biosci. Biotechnol. Biochem. 72: 2723-2731. PMID 18838797.
- ↑ Matsushita, K., Yakushi, T., Toyama, H., Shinagawa, E. and Adachi, O. (1996). „Function of multiple heme c moieties in intramolecular electron transport and ubiquinone reduction in the quinohemoprotein alcohol dehydrogenase-cytochrome c complex of Gluconobacter suboxydans”. J. Biol. Chem. 271: 4850-4857. PMID 8617755.
- ↑ Matsushita, K., Takaki, Y., Shinagawa, E., Ameyama, M. and Adachi, O. (1992). „Ethanol oxidase respiratory chain of acetic acid bacteria. Reactivity with ubiquinone of pyrroloquinoline quinone-dependent alcohol dehydrogenases purified from Acetobacter aceti and Gluconobacter suboxydans”. Biosci. Biotechnol. Biochem. 56: 304-310.
- ↑ Matsushita, K., Toyama, H. and Adachi, O. (1994). „Respiratory chains and bioenergetics of acetic acid bacteria”. Adv. Microb. Physiol. 36: 247-301. PMID 7942316.
- ↑ Cozier, G.E., Giles, I.G. and Anthony, C. (1995). „The structure of the quinoprotein alcohol dehydrogenase of Acetobacter aceti modelled on that of methanol dehydrogenase from Methylobacterium extorquens”. Biochem. J. 308: 375-379. PMID 7772016.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.