alfa-Tokoferol

α-Tokoferol
	(2R)-2,5,7,8-Tetrametil-2-[(4R,8R)-(4,8,12-trimetiltridecil)]-6-hromanol
Identifikacija
CAS registarski broj	59-02-9
PubChem	14985
ChemSpider	14265
UNII	N9PR3490H9
EINECS broj	200-412-2
DrugBank	DB00163
ChEBI	18145
ChEMBL	CHEMBL47
ATC code	A11HA03
Jmol-3D slike	Slika 1; Slika 2
SMILES
	Oc2c(c(c1O[C@](CCc1c2C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C)C Cc1c(c2c(c(c1O)C)CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C
InChI
	InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1 ; Kod: GVJHHUAWPYXKBD-IEOSBIPESA-N InChI=1/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1; Kod: GVJHHUAWPYXKBD-IEOSBIPEBS
Svojstva
Molekulska formula	C29H50O2
Molarna masa	430,71 g/mol
Agregatno stanje	žuto-smeđa viskozna tečnost
Gustina	0,950 g/cm3
Tačka topljenja	2.5–3.5 °C
Tačka ključanja	200–220 °C na 0,1 mmHg
Opasnost
NFPA 704	1 1 0
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

α-Tokoferol je tip tokoferola ili vitamina E. Njegov E broj je "E307".

α-Tokoferol je forma vitamina E koja se preferentno apsorbuje i akumulira kod ljudi.^[6] Određivanje aktivnosti vitamina E se bazira na poboljšanju plodnosti putem prevencije spontanog pobačaja kod skotnih pacova u odnosu na alfa-tokoferol.

Reference[uredi | uredi kod]

↑ Merck Index, 11th Edition, 9931.
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Rigotti A (2007). „Absorption, transport, and tissue delivery of vitamin E”. Mol. Aspects Med. 28 (5–6): 423–36. DOI:10.1016/j.mam.2007.01.002. PMID 17320165.

Spoljašnje veze[uredi | uredi kod]

Portal Hemija

[1] Merck Index, 11th Edition, 9931.

[2] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[3] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[4] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Rigotti A (2007). „Absorption, transport, and tissue delivery of vitamin E”. Mol. Aspects Med. 28 (5–6): 423–36. DOI:10.1016/j.mam.2007.01.002. PMID 17320165.

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alfa-Tokoferol

Reference[uredi | uredi kod]

Spoljašnje veze[uredi | uredi kod]

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