Alfa-N-acetilglukozaminidaza
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| Alfa-N-acetilglukozaminidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.50 | ||||||||
| CAS broj | 37288-40-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Alfa-N-acetilglukozaminidaza (EC 3.2.1.50, alfa-acetilglukozaminidaza, N-acetil-alfa-D-glukozaminidaza, N-acetil-alfa-glukozaminidaza, alfa-D-2-acetamido-2-dezoksiglukozidaza) je enzim sa sistematskim imenom alfa-N-acetil-D-glukozaminid N-acetilglukosaminohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza terminalnih neredukujućih N-acetil-D-glukozaminskih ostataka u N-acetil-alfa-D-glukozaminidima
Ovaj enzim hidrolizuje UDP-N-acetilglukozamin.
Reference[uredi | uredi kod]
- ↑ von Figura, K. (1977). „Human α-N-acetylglucosaminidase. 1. Purification and properties”. Eur. J. Biochem. 80: 523-533. PMID 411658.
- ↑ von Figura, K. (1977). „Human α-N-acetylglucosaminidase. 2. Activity towards natural substrates and multiple recognition forms”. Eur. J. Biochem. 80: 535-542. PMID 923593.
- ↑ Weissmann, B., Rowen, G., Marshall, J. and Friederici, D. (1967). „Mammalian α-acetylglucosaminidase. Enzymic properties, tissue distribution, and intracellular localization”. Biochemistry 6: 207-214. PMID 4291567.
- ↑ Werries, E., Wollek, E., Gottschalk, A. and Buddecke, E. (1969). „Separation of N-acetyl-α-glucosaminidase and N-acetyl-α-galactosaminidase from ox spleen. Cleavage of the O-glycosidic linkage between carbohydrate and polypeptide in ovine and bovine submaxillary glycoprotein by N-acetyl-α-galactosaminidase”. Eur. J. Biochem. 10: 445-449. PMID 5348072.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.