Adapalen

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Adapalen
(IUPAC) ime
6-[3-(adamantan-1-il)-4-metoksifenil]naftalen-2-karboksilna kiselina
Klinički podaci
Robne marke Adaferin, Differin
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 106685-40-9
ATC kod D10AD03
PubChem[1][2] 60164
DrugBank DB00210
ChemSpider[3] 54244
ChEMBL[4] CHEMBL31174 YesY
Hemijski podaci
Formula C28H28O3 
Mol. masa 412.5201
SMILES eMolekuli & PubHem
Farmakokinetički podaci
Izlučivanje Bolijarno
Farmakoinformacioni podaci
Trudnoća ?
Pravni status
Način primene Topikalno

Adapalen je topikalni retinoid koji se prvenstveno koristi u tretmanu akni . On je u prodaji pod imenom Differin u više zemalja.[5][6][7]

Reference[uredi - уреди | uredi izvor]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777.  edit
  5. Rolewski SL: Clinical review: topical retinoids. Dermatol Nurs. 2003 Oct;15(5):447-50, 459-65. PMID 14619325
  6. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). "DrugBank 3.0: a comprehensive resource for omics research on drugs". Nucleic Acids Res. 39 (Database issue): D1035–41. PMID 21059682. 
  7. Nucleic Acids Res (2008). "DrugBank: a knowledgebase for drugs, drug actions and drug targets" 36 (Database issue). pp. D901–6. PMID 18048412. 

Spoljašnje veze[uredi - уреди | uredi izvor]

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