Acil-(acil-nosilac-protein) desaturaza
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| Acil-(acil-nosilac-protein) desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.19.2 | ||||||||
| CAS broj | 37256-86-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acil-(acil-nosilac-protein) desaturaza (EC 1.14.19.2, desaturaza stearil acilnog prenosnog proteina, stearil-ACP desaturaza, acil-(acil-nosilac-protein), vodonik-donor:kiseonik oksidoreduktaza) je enzim sa sistematskim imenom acil-(acil-nosilac protein),vodonik-donor:kiseonik oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- stearoil-[acil-nosilac protein] + redukovani akceptor + O2 oleoil-[acil-nosilac protein] + akceptor + 2H2O
Enzim iz šafranike je specifičan za stearoil-[acil-nosilac protein]. Enzim iz Euglena deluje na derivate brojnih dugolančanih masnih kiselina.
Reference[uredi | uredi kod]
- ↑ Jaworski, J.G. and Stumpf, P.K. (1974). „Fat metabolism in higher plants. Properties of a soluble stearyl-acyl carrier protein desaturase from maturing Carthamus tinctorius”. Arch. Biochem. Biophys. 162: 158-165. PMID 4831331.
- ↑ Nagai, J. and Bloch, K. (1968). „Enzymatic desaturation of stearyl acyl carrier protein”. J. Biol. Chem. 243: 4626-4633. PMID 4300868.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.