Acetat-KoA ligaza
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Acetat-KoA ligaza | |||||||||
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Identifikatori | |||||||||
EC broj | 6.2.1.1 | ||||||||
CAS broj | 9012-31-1 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acetat-KoA ligaza (EC 6.2.1.1, acetil-KoA sintetaza, acetil aktivirajući enzim, acetatna tiokinaza, acil-aktivirajući enzim, acetil koenzim A sintetaza, acetil tiokinaza, acetil KoA ligaza, acetil KoA sintaza, acetil-koenzim A sintaza, kratkolančana masna acil-KoA sintetaza, kratkolačana acil-koenzim A sintetaza, ACS) je enzim sa sistematskim imenom acetat:KoA ligaza (formira AMP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim takođe deluje na propanoat i propenoat.
Reference[uredi | uredi kod]
- ↑ Chou, T.C. and Lipmann, F. (1952). „Separation of acetyl transfer enzymes in pigeon liver extract”. J. Biol. Chem. 196: 89-103. PMID 12980945.
- ↑ Eisenberg, M.A. (1955). „The acetate-activating enzyme of Rhodospirillum rubrum”. Biochim. Biophys. Acta 16: 58-65. PMID 14363230.
- ↑ Hele, P. (1954). „The acetate activating enzyme of beef heart”. J. Biol. Chem. 206: 671-676. PMID 13143026.
- ↑ Millerd, A. and Bonner, J. (1954). „Acetate activation and acetoacetate formation in plant systems”. Arch. Biochem. Biophys. 49: 343-355. PMID 13159282.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.