6-Oksocineol dehidrogenaza
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| 6-Oksocineol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.51 | ||||||||
| CAS broj | 122933-80-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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6-Oksocineol dehidrogenaza (EC 1.14.13.51, 6-oksocineolna oksigenaza) je enzim sa sistematskim imenom 6-oksocineol,NADPH:kiseonik oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 6-oksocineol + NADPH + H+ + O2 1,6,6-trimetil-2,7-dioksabiciklo[3.2.2]-nonan-3-on + NADP+ +H2O
Produkt podleže neenzimatskom razlaganju i naknadnom zatvaranju prstena čime se formira lakton 4,5-dihidro-5,5-dimetil-4-(3-oksobutil)furan-2(3H)-on.
Reference[uredi | uredi kod]
- ↑ Williams, D.R., Trudgill, P.W. and Taylor, D.G. (1989). „Metabolism of 1,8-cineole by Rhodococcus species: ring cleavage reactions”. J. Gen. Microbiol. 135: 1957-1967.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.